Project Description

Global Trainee Program

Proteins Structure and Function: The driving force behind R&D models of biotechnology industries

 Biotechnology

Course ID – GKA-081

Learning Outcome

Proteins are the molecular workforce in all the biological systems as they perform and regulate essential functions from DNA replication to metabolic pathways. Therefore, understanding of their structure and function holds significant importance for biologists.

Career Impact of this Project

This internship will provide students practical overview and hands-on experience of various tools/databases freely available which can be used for detailed protein analysis from sequence to structure to function. These skills will help students spending moretime on analysis rather experimenting on bench. Eventually this can lead to quicker and efficient experimental planning which is necessary for future careers both in academics as well as industry.

Most of the R&D in biotech/pharma industries is based on drug discovery, immunology, antibodies, proteins and peptides, enzymes and inhibitors. Thus, this project/course can be extremely beneficial for students seeking future careers in industry.

Enquire Today

Global Trainee Program

Proteins Structure and Function: The driving force behind R&D models of biotechnology industries

 Biotechnology

Course ID – GKA-081

What will be covered in 8 weeks during the project

Week 1

Protein structure – understanding protein components-amino acids, primary, secondary, tertiary and quaternary structure, folding in to 3 – dimensional entities

Week 2

Examining the protein sequence – function, class of protein, Uniprot & InterPro tools, cellular localization

Week 3

Understanding Enzymes and Inhibitor families (Uniprot & Interpro) databases

Week 4

Protein biochemical characterization – concentration, molecular weight, isoelectric point, stability, solubility, specificity of enzymes

Week 5

Designing the strategy for purification of a specific protein – Affinity, ionexchange, size exclusion chromatography

Week 6

Biophysical characterization techniques & Introduction to protein structureanalysis – PDB and other resources

Week 7

Finding homologs, visualizing structures, comparing protein structures, effects of mutations.

Week 8

Homology modelling and structure prediction, hands-on with a protein of your choice.

Enquire Today

Global Trainee Program

Proteins Structure and Function: The driving force behind R&D models of biotechnology industries

 Biotechnology

Course ID – GKA-081

Internship Format

In the virtual internship, the week would begin with live video session with the mentor / subject matter expert on the topic/s of the week. For completing the week’s tasks and assignments, the trainees will provided all the knowledge and information required, guidance on what has to be done and resources, if any. The students work (in teams) on their tasks and submit their work by the weekly deadline. They can seek any clarifications, queries, help anytime during the week if they face any difficulties.

The trainees can expect to input 40 hours of work every week.

At the end of 8 weeks, trainees will be expected to submit an internship report as the final outcome of their work.

Program Duration and Cost

4 Weeks – USD 130

8 Weeks – USD 260

Limited number of scholarships are available on a first come first serve basis through Ureka Foundation.

Enquire Today

 

Become Part of Global Knowledge Alliance to Further Your Career.